Treatment outcome in infant acute lymphoblastic leukemia
نویسندگان
چکیده
منابع مشابه
Infant Acute Lymphoblastic Leukemia
Acute lymphoblastic leukemia (ALL) in infants under 12 months of age accounts for about 4% of childhood ALL and differs from ALL in older children with respect to immunophenotypic, cytogenetic and molecular genetic features. In contrast to the predominance of male sex in older children with ALL, there is a slight predominance of girls in infant ALL (1). In infant leukemia, all necessary genetic...
متن کاملPrednisone response is the strongest predictor of treatment outcome in infant acute lymphoblastic leukemia.
To define prognostic factors in infant acute lymphoblastic leukemia (ALL), the outcome of 106 infants (age </=12 months) during 3 consecutive multicenter trials of the Berlin-Frankfurt-Münster group (ALL-BFM 83, 86, and 90) was retrospectively analyzed according to presenting features and early in vivo response to prednisone. The prednisone response was defined as the cytoreduction (number of b...
متن کاملHyperleukocytosis in childhood acute lymphoblastic leukemia: complications and treatment outcome.
Hyperleukocytosis, defined as a peripheral leukocyte count ≥ 100x109/L, is seen in 5-20% of newly diagnosed cases of childhood leukemia and is a poor prognostic factor. In this study, we aimed to examine the presenting clinical and laboratory features, complications, and treatment outcome of 47 children with acute lymphoblastic leukemia (ALL) and hyperleukocytosis who were diagnosed and treated...
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ژورنال
عنوان ژورنال: Blood
سال: 2000
ISSN: 1528-0020,0006-4971
DOI: 10.1182/blood.v95.8.2729.008a36b_2729_2729